Hydroquinone-Works But Is It Safe?

Hydroquinone is one of the most used topical agents for the treatment of hyperpigmentation. It has proven to be an effective skin lightener by many clinical trials over the years. It works by inhibiting the enzyme tyrosinase, which blocks part of the synthesis of melanin (dark skin pigment). Hydroquinone usually takes several weeks to start showing results. This is because the existing melanin needs time to migrate out of the skin. You can decrease the time by including an exfoliation treatment but this can cause irritation especially if you have sensitive skin.

Hydroquinone is available over the counter in 2% strength or you can get a 4% strength product but you’ll need a prescription. Side effects are reported to be mild and non-systemic at the lower strength products.

The issue with Hydroquinone is the fact that in animal studies of high doses there was a potential to cause cancer. There are also reports that hydroquinone can in rare cases with low strength concentrations cause ochronosis, a bluish black discoloration of tissue.  However darker skinned people who use the higher strength products for a prolonged time seem to have more frequent cases of ochronosis. This has cause hydroquinone to be banned in some countries.

Just because animal studies of high strengthen prolonged use of hydroquinone increase the chance of cancer does not necessarily mean that normal usage of over the counter products will have the same effect on humans. In fact hydroquinone has been available to the public for decades so you can assume that it is fairly safe if used as directed.

If you are concerned with the possible risk that may or may not be associated with hydroquinone there are now several  all-natural product that do not include hydroquinone that have showed good results in treating hyperpigmentation. These products such as Meladerm use Kojic acid, Glycolc acid, lemon juice extract, Gigawhite, and other naturally occurring ingredients that help lighten the skin.

Whichever product you decide to try it is advised to talk to a dermatologist to ensure your safety.